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RET-IN-3
CAS No. 2414374-53-9
RET-IN-3( —— )
Catalog No. M37651 CAS No. 2414374-53-9
RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 144 | Get Quote |
|
| 5MG | 217 | Get Quote |
|
| 10MG | 345 | Get Quote |
|
| 25MG | 625 | Get Quote |
|
| 50MG | 984 | Get Quote |
|
| 100MG | 1485 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRET-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionRET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.
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DescriptionRET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM.
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In VitroRET-IN-3 exhibits 16 and 410 fold selectivity compared to wt-RET and KDR, respectively.
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In Vivo——
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Synonyms——
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PathwayTyrosine Kinase
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Targetc-RET
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Recptorc-RET
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Research Area——
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Indication——
Chemical Information
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CAS Number2414374-53-9
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Formula Weight339.39
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Molecular FormulaC18H21N5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (294.65 mM; Ultrasonic )
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SMILESCN(C)CCCNc1ccn2ncc(-c3ccc4OCOc4c3)c2n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET V804M Kinase. ACS Med Chem Lett. 2020 Feb 28;11(4):497-505.?
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RET-IN-3
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