R-IMPP

CAS No. 2133832-83-2

R-IMPP ( —— )

Catalog No. M17432 CAS No. 2133832-83-2

R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 49 Get Quote
5MG 77 Get Quote
10MG 135 Get Quote
25MG 281 Get Quote
50MG 500 Get Quote
100MG 718 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    R-IMPP
  • Note
    Research use only, not for human use.
  • Brief Description
    R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
  • Description
    R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PCSK9
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    2133832-83-2
  • Formula Weight
    389.21
  • Molecular Formula
    C24H27N3O2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 41 mg/mL; 105.27 mM
  • SMILES
    COC1=CC=C(CCC(N(C2=C(C=CC=C3)C3=CC=N2)[C@H]4CNCCC4)=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Petersen DN., et al. A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation. Cell Chem Biol. 2016 Nov 17;23(11):1362-1371.
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