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R-IMPP

CAS No. 2133832-83-2

R-IMPP ( —— )

Catalog No. M17432 CAS No. 2133832-83-2

R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 49 Get Quote
5MG 77 Get Quote
10MG 135 Get Quote
25MG 281 Get Quote
50MG 500 Get Quote
100MG 718 Get Quote
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Biological Information

  • Product Name
    R-IMPP
  • Note
    Research use only, not for human use.
  • Brief Description
    R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
  • Description
    R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PCSK9
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    2133832-83-2
  • Formula Weight
    389.21
  • Molecular Formula
    C24H27N3O2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 41 mg/mL; 105.27 mM
  • SMILES
    COC1=CC=C(CCC(N(C2=C(C=CC=C3)C3=CC=N2)[C@H]4CNCCC4)=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Petersen DN., et al. A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation. Cell Chem Biol. 2016 Nov 17;23(11):1362-1371.
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