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FFN 511
CAS No. 1004548-96-2
FFN 511( —— )
Catalog No. M33849 CAS No. 1004548-96-2
Fluorescent false neurotransmitter (FFN)
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 144 | In Stock |
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| 10MG | 236 | In Stock |
|
| 25MG | 468 | In Stock |
|
| 50MG | 662 | In Stock |
|
| 100MG | 923 | In Stock |
|
| 200MG | 1237 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFFN 511
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NoteResearch use only, not for human use.
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Brief DescriptionFluorescent false neurotransmitter (FFN)
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DescriptionFFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2-containing membranes with an IC50 of 1 μM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices.
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In VitroFFN511 (350 nM; 30 min) accumulats in a pattern consistent with LDCVs in cultured mouse chromaffin cells, and the accumulation is abolished by the lipophilic base chloroquine.Cell Viability Assay Cell Line:mouse chromaffin cells Concentration:350 nM Incubation Time:30 min Result:Accumulated in cultured mouse chromaffin cells (the same as LDCVs), and the accumulation could be abolished by the lipophilic base chloroquine, which collapses the vesicle pH gradient.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1004548-96-2
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Formula Weight284.35
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Molecular FormulaC17H20N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1OC2=C(C=C3C4=C2CCCN4CCC3)C(=C1)CCN
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gubernator NG, et al. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science. 2009 Jun 12;324(5933):1441-4.?
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