Pyroxamide

CAS No. 382180-17-8

Pyroxamide ( —— )

Catalog No. M20956 CAS No. 382180-17-8

Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 39 Get Quote
10MG 68 Get Quote
25MG 146 Get Quote
50MG 251 Get Quote
100MG 443 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Pyroxamide
  • Note
    Research use only not for human use.
  • Brief Description
    Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).
  • Description
    Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    382180-17-8
  • Formula Weight
    265.31
  • Molecular Formula
    C13H19N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (471.15 mM)
  • SMILES
    O=C(CCCCCCC(=O)Nc1cccnc1)NO
  • Chemical Name
    N1-hydroxy-N8-(pyridin-3-yl)octanediamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Butler L M Webb Y Agus D B et al. Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide an inhibitor of histone deacetylase[J]. Clinical Cancer Research 2001 7(4):962-970.
molnova catalog
related products
  • SKLB-23bb

    SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability.

  • BRD6688

    BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes.

  • Exifone

    Exifone is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increased relative maximal rate of HDAC1-catalyzed deacetylation.