Prulifloxacin ( NM441;AF 3012;Pruvel )

Catalog No. M20132 CAS No. 123447-62-1

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Product Name

Prulifloxacin
Note

Research use only not for human use.
Brief Description

Prulifloxacin is a broad-spectrum fluoroquinolone antibiotic. It Inhibits bacterial DNA synthesis by inhibiting the activity of bacterial DNA topoisomerase II and IV.
Description

Prulifloxacin is a broad-spectrum fluoroquinolone antibiotic. It Inhibits bacterial DNA synthesis by inhibiting the activity of bacterial DNA topoisomerase II and IV.
Synonyms

NM441;AF 3012;Pruvel
Pathway

Cell Cycle/DNA Damage
Target

Topoisomerase
Recptor

Topo II; Topo IV
Research Area

Infection
Indication

Acute exacerbations of chronic bronchitis; Bacterial infections; Pneumonia; Respiratory tract infections; Urinary tract infections

CAS Number

123447-62-1
Formula Weight

461.46
Molecular Formula

C21H20FN3O6S
Purity

>98% (HPLC)
Solubility

DMSO: 15 mg/mL (32.5 mM);Water: Insoluble
SMILES

CC1Sc2c(C(O)=O)c(=O)c3cc(F)c(cc3n12)N1CCN(Cc2oc(=O)oc2C)CC1
Chemical Name

6-fluoro-1-methyl-7-(4-((5-methyl-2-oxo-13-dioxol-4-yl)methyl)piperazin-1-yl)-4-oxo-1H4H-[13]thiazeto[32-a]quinoline-3-carboxylic acid

1.Giannarini G et al. Prulifloxacin: clinical studies of a broad-spectrum quinolone agent. Future Microbiol. 2009 Feb;4(1):13-24.

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