Amsacrine hydrochloride

CAS No. 54301-15-4

Amsacrine hydrochloride( m-AMSA hydrochloride | acridinyl anisidide hydrochloride )

Catalog No. M20463 CAS No. 54301-15-4

Amsacrine hydrochloride is topoisomerase II inhibitor is used in the treatment of acute myelogenous leukemia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 37 In Stock
25MG 51 In Stock
50MG 67 In Stock
100MG 90 In Stock
200MG 117 In Stock
500MG 166 In Stock
1G 244 In Stock

Biological Information

  • Product Name
    Amsacrine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Amsacrine hydrochloride is topoisomerase II inhibitor is used in the treatment of acute myelogenous leukemia.
  • Description
    Amsacrine hydrochloride is topoisomerase II inhibitor is used in the treatment of acute myelogenous leukemia.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    m-AMSA hydrochloride | acridinyl anisidide hydrochloride
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Topoisomerase
  • Research Area
    Cancer
  • Indication
    acute myelogenous leukemia

Chemical Information

  • CAS Number
    54301-15-4
  • Formula Weight
    429.92
  • Molecular Formula
    C21H20ClN3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (145.38 mM)
  • SMILES
    Cl.COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Thomas D Hammerling B C Wu K et al. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action[J]. British Journal of Pharmacology 2004 142(3):485-494.
molnova catalog
related products
  • UAMC 00039 dihydroch...

    UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.

  • Aclacinomycin A

    Aclacinomycin A (Aclarubicin) is a novel anthracycline antibiotic isolated from Streptomyces galilei with antitumor activity.

  • Hydroxy Camptothecin...

    An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata.