
Propylthiouracil
CAS No. 51-52-5
Propylthiouracil( NSC 6498 | NSC 70461 | 6-n-Propylthiouracil | PTU )
Catalog No. M14789 CAS No. 51-52-5
Propylthiouracil is a Thyroid Hormone Synthesis Inhibitor.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
25MG | 30 | In Stock |
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50MG | 41 | In Stock |
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100MG | 52 | In Stock |
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200MG | 65 | In Stock |
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500MG | 78 | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NamePropylthiouracil
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NoteResearch use only, not for human use.
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Brief DescriptionPropylthiouracil is a Thyroid Hormone Synthesis Inhibitor.
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DescriptionPropylthiouracil is a Thyroid Hormone Synthesis Inhibitor. A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism.
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In VitroCell Viability Assay Cell Line:U-937 cells Concentration:5.5 μg/mL, 11 μg/mL, 110 μg/mL, 220 μg/mL, 330 μg/mL Incubation Time:24 hours Result:Induced cytotoxicity in a dose-dependent manner.
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In VivoAnimal Model:Adult C57BL/6J and wild-derived WSB/EiJ male mice (8-weeks old)Dosage:1.5 g/kg diet Administration:Iodine-deficient diet; for 7 weeks Result:Induced hypothyroidism in adult C57BL/6J and wild-derived WSB/EiJ male mice.
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SynonymsNSC 6498 | NSC 70461 | 6-n-Propylthiouracil | PTU
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PathwayEndocrinology/Hormones
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TargetTHR
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RecptorThyroid peripheral conversion
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Research AreaEndocrinology
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Indication——
Chemical Information
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CAS Number51-52-5
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Formula Weight170.24
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Molecular FormulaC7H10N2OS
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Purity>98% (HPLC)
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SolubilityEthanol: 19 mg/mL (111.61 mM); DMSO: 34 mg/mL (199.72 mM)
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SMILESCCCC1=CC(=O)NC(=S)N1
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Chemical Name6-(2,2,3,3,3-pentadeuteriopropyl)-2-sulfanylidene-1H-pyrimidin-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sugawara M, et al. Thyroid. 1999 May;9(5):513-8.
molnova catalog



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