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Pico145
CAS No. 1628287-16-0
Pico145 ( HC-608 )
Catalog No. M23723 CAS No. 1628287-16-0
Pico145 is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits (?)-englerin A-activated TRPC4/TRPC5 channels.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 262 | In Stock |
|
| 10MG | 411 | In Stock |
|
| 25MG | 678 | In Stock |
|
| 50MG | 954 | In Stock |
|
| 100MG | 1287 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePico145
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NoteResearch use only, not for human use.
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Brief DescriptionPico145 is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits (?)-englerin A-activated TRPC4/TRPC5 channels.
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DescriptionPico145 is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits (?)-englerin A-activated TRPC4/TRPC5 channels (IC50s: 0.349 and 1.3 nM in cells) It also shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
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SynonymsHC-608
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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RecptorTRPC4, cell assay;TRPC5, cell assay;TRPC4-TRPC1, cell assay;TRPC5-TRPC1, cell assay
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Research Area——
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Indication——
Chemical Information
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CAS Number1628287-16-0
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Formula Weight524.9
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Molecular FormulaC23H20ClF3N4O5
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Purity>98% (HPLC)
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SolubilityDMSO : 99 mg/mL (188.61 mM)
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SMILESCN(c1c(C(N2CCCO)=O)n(Cc(cc3)ccc3Cl)c(Oc3cc(OC(F)(F)F)ccc3)n1)C2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rubaiy HN, et al. Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels. J Biol Chem. 2017 May 19;292(20):8158-8173.
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