N-Ethyl-p-menthane-3-carboxamide

CAS No. 39711-79-0

N-Ethyl-p-menthane-3-carboxamide ( TRPM8 antagonist WS-3;Cyclohexanecarboxamide;N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide )

Catalog No. M20582 CAS No. 39711-79-0

N-Ethyl-p-menthane-3-carboxamide is an agonist of TRPM8( EC50 : 3.7 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1G 27 In Stock

Biological Information

  • Product Name
    N-Ethyl-p-menthane-3-carboxamide
  • Note
    Research use only not for human use.
  • Brief Description
    N-Ethyl-p-menthane-3-carboxamide is an agonist of TRPM8( EC50 : 3.7 μM).
  • Description
    N-Ethyl-p-menthane-3-carboxamide is an agonist of TRPM8( EC50 : 3.7 μM).
  • Synonyms
    TRPM8 antagonist WS-3;Cyclohexanecarboxamide;N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    TRPM8
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    39711-79-0
  • Formula Weight
    211.34
  • Molecular Formula
    C13H25NO
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (473.17 mM)
  • SMILES
    CCNC(=O)C1CC(C)CCC1C(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.H‐J Behrendt Germann T Gillen C et al. Characterization of the mouse cold‐menthol receptor TRPM8 and vanilloid receptor type‐1 VR1 using a fluorometric imaging plate reader (FLIPR) assay[J]. British Journal of Pharmacology 2004 141(4).
molnova catalog
related products
  • JNJ-38893777 sulfate

    JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.

  • CIM0216

    CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.

  • BI-749327

    BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).