Pentagastrin ( Pentagastrin; NCGC00183362-01; Pentagastrinum; Peptavlon )

Catalog No. M18800 CAS No. 5534-95-2

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Datasheet

HNMR

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Product Name

Pentagastrin
Note

Research use only, not for human use.
Brief Description

pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally, which can cause the secretion and synthesis of salivary proteins.
Description

Pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid as the pentagastrin-stimulated calcitonin test. Pentagastrin binds to the cholecystokinin-B receptor, which is expressed widely in the brain. Activation of these receptors activates the phospholipase C second messenger system.
Synonyms

Pentagastrin; NCGC00183362-01; Pentagastrinum; Peptavlon
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Cancer
Indication

——

CAS Number

5534-95-2
Formula Weight

767.89
Molecular Formula

C37H49N7O9S
Purity

98%
Solubility

DMSO : ≥ 34 mg/mL; 44.28 mM
SMILES

CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCNC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Chemical Name

(3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoylamino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoic acid

1.Loy F,etal.Ultrastructural evidence of a secretory role for melatonin in the human parotid gland.J Physiol Pharmacol. 2015 Dec;66(6):847-53.

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