PU-WS13

CAS No. 1454619-14-7

PU-WS13( PU-WS-13 )

Catalog No. M11960 CAS No. 1454619-14-7

A potent and selective Grp94 inhibitor with Ic50 of 0.22 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PU-WS13
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective Grp94 inhibitor with Ic50 of 0.22 uM.
  • Description
    A potent and selective Grp94 inhibitor with Ic50 of 0.22 uM; shows >35 fold selectivity over other four HSP90 paralogs, Hsp90α, Hsp90β and Trap-1 (IC50> 7 uM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PU-WS-13
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1454619-14-7
  • Formula Weight
    411.3519
  • Molecular Formula
    C17H20Cl2N6S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 40 mg/mL
  • SMILES
    NC1=C2N=C(SC3=CC(Cl)=CC(Cl)=C3)N(CCCNC(C)C)C2=NC=N1
  • Chemical Name
    9H-Purine-9-propanamine, 6-amino-8-[(3,5-dichlorophenyl)thio]-N-(1-methylethyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Patel PD, et al. Nat Chem Biol. 2013 Nov;9(11):677-84.
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