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ACO1
CAS No. 2065198-79-8
ACO1( ACO 1 )
Catalog No. M13211 CAS No. 2065198-79-8
ACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameACO1
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NoteResearch use only, not for human use.
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Brief DescriptionACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM.
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DescriptionACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM, displays >200-fold selectivity against other Hsp90 isoforms; exhibits a significant decrease in mutatnt myocilin I477N levels at 30 uM in tetracycline inducible HEK cells; inhibits the migration of MDA-MB-231 and PC-3 MM-2 at 10 uM and 5 uM,respectively.
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In Vitro——
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In Vivo——
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SynonymsACO 1
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetHSP
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RecptorHSP
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Research Area——
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Indication——
Chemical Information
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CAS Number2065198-79-8
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Formula Weight405.498
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Molecular FormulaC24H27N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name4-(2-(2-hydroxybenzyl)-1H-pyrrol-1-yl)-2-(((1r,4r)-4-hydroxycyclohexyl)amino)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mishra SJ, et al. ACS Chem Biol. 2017 Jan 20;12(1):244-253.
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