PU-H71

CAS No. 873436-91-0

PU-H71( NSC 750424 )

Catalog No. M19535 CAS No. 873436-91-0

PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM. Phase 1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 53 Get Quote
10MG 74 Get Quote
25MG 118 Get Quote
50MG 178 Get Quote
100MG 319 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PU-H71
  • Note
    Research use only, not for human use.
  • Brief Description
    PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM. Phase 1.
  • Description
    PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM. Phase 1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 750424
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP90
  • Research Area
    Cancer
  • Indication
    Breast Cancer; Myelofibrosis; Pancreatic Cancer

Chemical Information

  • CAS Number
    873436-91-0
  • Formula Weight
    512.37
  • Molecular Formula
    C18H21IN6O2S
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 100 mg/mL (195.17 mM);DMSO: 100 mg/mL (195.17 mM);Water: 34 mg/mL (66.35 mM) warmed
  • SMILES
    CC(C)NCCCN1C(SC2=CC3=C(OCO3)C=C2I)=NC2=C(N)N=CN=C12 |c:18212326t:101228|
  • Chemical Name
    8-((6-iodobenzo[d][13]dioxol-5-yl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Caldas-Lopes E et al. Proc Natl Acad Sci U S A 2009 106(20) 8368-8373.
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