PNZ5

CAS No. 1629277-36-6

PNZ5( —— )

Catalog No. M26388 CAS No. 1629277-36-6

PNZ5 is a potent and isoxazole-based pan-BET inhibitor, with high selectivity and potency similar to the well-established (+)-JQ1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 264 Get Quote
5MG 404 Get Quote
10MG 593 Get Quote
25MG 888 Get Quote
50MG 1251 Get Quote
100MG 1692 Get Quote
500MG 3402 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PNZ5
  • Note
    Research use only, not for human use.
  • Brief Description
    PNZ5 is a potent and isoxazole-based pan-BET inhibitor, with high selectivity and potency similar to the well-established (+)-JQ1.
  • Description
    PNZ5 is a potent and isoxazole-based pan-BET inhibitor, with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1629277-36-6
  • Formula Weight
    318.376
  • Molecular Formula
    C20H18N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [H][C@]1(N(C)C(=O)c2ccc(cc12)-c1c(C)noc1C)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ye, C., Jin, M., Jin, C. et al. Inhibitory Effects of Chemical Constituents from Actinidia kolomikta on LPS-Induced Inflammatory Responses. Rev. Bras. Farmacogn. 30, 127–131 (2020).
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