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PKC-IN-7
CAS No. 860468-10-6
PKC-IN-7( —— )
Catalog No. M16235 CAS No. 860468-10-6
PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NamePKC-IN-7
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NoteResearch use only, not for human use.
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Brief DescriptionPKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM.
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DescriptionPKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC
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Research Area——
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Indication——
Chemical Information
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CAS Number860468-10-6
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Formula Weight443.931
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Molecular FormulaC26H22ClN3O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name3-(2-chloro-7-((dimethylamino)methyl)naphthalen-1-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. van Eis MJ, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):781-786.
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