PF-06873600

CAS No. 2185857-97-8

PF-06873600 ( PF06873600;PF 06873600 )

Catalog No. M13486 CAS No. 2185857-97-8

PF-06873600 (PF06873600, PF 06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 254 Get Quote
10MG 403 Get Quote
25MG 762 Get Quote
50MG 1017 Get Quote
100MG 1377 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PF-06873600
  • Note
    Research use only, not for human use.
  • Brief Description
    PF-06873600 (PF06873600, PF 06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively.
  • Description
    PF-06873600 (PF06873600, PF 06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively; demonstrates potential antineoplastic activity, incerease apoptosis and inhibits umor cell proliferation.Breast Cancer Phase 2 Clinical
  • Synonyms
    PF06873600;PF 06873600
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CDK
  • Research Area
    Cancer
  • Indication
    Breast Cancer

Chemical Information

  • CAS Number
    2185857-97-8
  • Formula Weight
    471.52
  • Molecular Formula
    C20H27F2N5O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 83.33 mg/mL 176.73 mM
  • SMILES
    O=C1C(C(F)F)=CC2=CN=C(NC3CCN(S(=O)(C)=O)CC3)N=C2N1[C@H]4[C@](C)(O)CCC4
  • Chemical Name
    Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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