Indisulam

Research use only, not for human use.

Indisulam (E7070) is potent, sulfonamide, cell-cycle inhibitor that possesses antiproliferative activities, causes decrease in the S phase fraction along with G1 and/or G2 accumulation in various cancer cell lines.

Indisulam (E7070) is potent, sulfonamide, cell-cycle inhibitor that possesses antiproliferative activities, causes decrease in the S phase fraction along with G1 and/or G2 accumulation in various cancer cell lines; causes blockade in the G1/S transition through inhibition of the activation of both cyclin-dependent kinase 2 and cyclin E, shows activity in multiple tumor types, most prominently in colon and lung cancer.Breast Cancer Phase 2 Discontinued

E 7070;E7070

Angiogenesis

CDK

carbonicanhydrase;CDK

Cancer

Breast Cancer

165668-41-7

385.85

C14H12ClN3O4S2

>98% (HPLC)

DMSO: 20mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)

O=S(C1=CC=C(S(=O)(N)=O)C=C1)(NC2=CC=CC3=C2NC=C3Cl)=O

N-(3-chloro-7-indolyl)-1,4-benzenedisulfonamide

(-20℃)

With Ice Pack

≥ 2 years