PF-04745637 ( —— )

Catalog No. M26002 CAS No. 1917294-46-2

PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	222	In Stock
10MG	311	In Stock
25MG	525	In Stock
50MG	750	In Stock
100MG	1035	In Stock
500MG	2061	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

PF-04745637
Note

Research use only, not for human use.
Brief Description

PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM.
Description

PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM.(In Vivo):PF-04745637 (topically applied; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin.
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

Immunology/Inflammation related
Research Area

——
Indication

——

Chemical Information

CAS Number

1917294-46-2
Formula Weight

509.0
Molecular Formula

C27H32ClF3N2O2
Purity

>98% (HPLC)
Solubility

——
SMILES

OC1(CCN(CC1)C(CNC(=O)C1(CCCC1)c1ccc(Cl)cc1)Cc1ccccc1)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Constituents of Compositae plants III. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers.Cancer Lett., 2002, 177(1):7-12.

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