Cart
sales@molnova.com
PF-00562271
CAS No. 939791-38-5
PF-00562271 ( —— )
Catalog No. M16725 CAS No. 939791-38-5
PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 67 | In Stock |
|
| 5MG | 108 | In Stock |
|
| 10MG | 135 | In Stock |
|
| 25MG | 224 | In Stock |
|
| 50MG | 332 | In Stock |
|
| 100MG | 494 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePF-00562271
-
NoteResearch use only, not for human use.
-
Brief DescriptionPF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM.
-
DescriptionPF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.
-
Synonyms——
-
PathwayAngiogenesis
-
TargetCDK
-
RecptorCDK1/CyclinB; CDK2/CyclinE; CDK3/CyclinE; FAK; PYK2
-
Research AreaCancer
-
IndicationSolid Tumors
Chemical Information
-
CAS Number939791-38-5
-
Formula Weight665.66
-
Molecular FormulaC21H20F3N7O3S.C6H6O3S
-
Purity>98%(HPLC)
-
SolubilityDMSO:14 mg/mL warmed (21.03 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
-
SMILESOS(=O)(=O)C1=CC=CC=C1.CN(C1=C(CNC2=C(C=NC(NC3=CC=C4NC(=O)CC4=C3)=N2)C(F)(F)F)C=CC=N1)S(C)(=O)=O |c:6,8,12,18,31,33,40,42,t:4,16,22,24|
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Roberts WG, et al. Cancer Res. 2008, 68(6), 1935-1944.
molnova catalog
related products
-
BAY 1251152
BAY 1251152 is the first potent, selective, orally available PTEFb/CDK9 inhibitor with biochemical IC50 of 9 nM and MOLM13 cell IC50 of 29 nM.
-
SNS-032
SNS-032 (BMS-387032)is a potent and selective inhibitor of CDK 2/7/9 with IC50 of 48 nM/62 nM/4 nM, respectively.
-
Ribociclib succinate
Ribociclib succinate is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.
