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Home - Products - Metabolic Enzyme/Protease - Retinoid Receptor - PA452

PA452

CAS No. 457657-34-0

PA452( —— )

Catalog No. M26781 CAS No. 457657-34-0

PA452 is a retinoic X receptor (RXR) specific antagonist. PA452 suppresses the effect of Retinoic acid (RA) on Th1/Th2 development.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PA452
  • Note
    Research use only, not for human use.
  • Brief Description
    PA452 is a retinoic X receptor (RXR) specific antagonist. PA452 suppresses the effect of Retinoic acid (RA) on Th1/Th2 development.
  • Description
    PA452 is a retinoic X receptor (RXR) specific antagonist. PA452 suppresses the effect of Retinoic acid (RA) on Th1/Th2 development.(In Vitro):PA452 suppresses the Troglitazone (TZ)-induced CK13 expression. In normal human urothelial (NHU) cells, PA452 (0.01-1 μM) inhibits retinoic X receptor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Retinoid Receptor
  • Recptor
    DPPH
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    457657-34-0
  • Formula Weight
    439.6
  • Molecular Formula
    C26H37N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 40 mg/mL (90.99 mM)
  • SMILES
    CCCCCCOc1cc2c(cc1N(C)c1ncc(cn1)C(O)=O)C(C)(C)CCC2(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cho MH, Paik YS, Hahn TR. Physical stability of shikonin derivatives from the roots of Lithospermum erythrorhizon cultivated in Korea. J Agric Food Chem. 1999 Oct;47(10):4117-20.
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