AC-55649( —— )

Catalog No. M33255 CAS No. 59662-49-6

AC-55649 is a potent and highly isoform-selective agonist of the human RARβ2 receptor, characterized by a pEC50 of 6.9.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

AC-55649
Note

Research use only, not for human use.
Brief Description

AC-55649 is a potent and highly isoform-selective agonist of the human RARβ2 receptor, characterized by a pEC50 of 6.9.
Description

AC-55649 is a potent, highly isoform-selective agonist of human RARβ2receptor, with a pEC50 of 6.9.
In Vitro

AC-55649 is a potent, highly isoform-selective agonist at the human RARβ2 receptor, with a pEC50 of 6.9. AC-55649 is a potent and selective activator of RARβ2 transcriptional activity.
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Retinoid Receptor
Recptor

Retinoid Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

59662-49-6
Formula Weight

310.43
Molecular Formula

C21H26O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (322.13 mM; Ultrasonic )
SMILES

CCCCCCCCc1ccc(cc1)-c1ccc(cc1)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lund BW, et al. Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. J Med Chem. 2005 Dec 1;48(24):7517-9.?

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