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P11
CAS No. 848644-86-0
P11 ( )
Catalog No. M30577 CAS No. 848644-86-0
Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameP11
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NoteResearch use only, not for human use.
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Brief DescriptionPotent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
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DescriptionPotent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
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Synonyms
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number848644-86-0
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Formula Weight720.8
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Molecular FormulaC30H48N12O9
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Purity>98% (HPLC)
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Solubilitywater:2 mg/mL
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SMILES[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(N)=O
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Chemical Name
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lee et al (2004) High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip. J.Biomol.Screen. 9 687 PMID:
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