Ouabain( NSC 25485 | Astrobain | Gratibain | Purostrophan )

Catalog No. M19456 CAS No. 630-60-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Ouabain
Note

Research use only, not for human use.
Brief Description

Ouabain is a selective Na+/K+ -ATPase inhibitor binds to α2 /α3 subunit with Ki of 41 nM/15 nM.
Description

Ouabain is a selective Na+/K+ -ATPase inhibitor binds to α2 /α3 subunit with Ki of 41 nM/15 nM.
In Vitro

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In Vivo

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Synonyms

NSC 25485 | Astrobain | Gratibain | Purostrophan
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

α3 α2
Research Area

——
Indication

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CAS Number

630-60-4
Formula Weight

728.77
Molecular Formula

C29H44O12·8H2O
Purity

>98% (HPLC)
Solubility

DMSO:93 mg/mL (127.6 mM);Ethanol:93 mg/mL (127.6 mM);Water:<1 mg/mL
SMILES

C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C2=CC(=O)OC2)[C@H](O)[C@H](O)[C@H]1O
Chemical Name

3-(6-Deoxy-alpha-L-mannopyranosyloxy)-1511a1419-pentahydroxycard-20(22)-enolide

1.Lucchesi PA et al. J Biol Chem 1991 266(14) 9327-9331.

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