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Benzamil (hydrochloride)
CAS No. 2898-76-2
Benzamil (hydrochloride)( —— )
Catalog No. M20570 CAS No. 2898-76-2
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 69 | In Stock |
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| 5MG | 48 | In Stock |
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| 10MG | 57 | In Stock |
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| 25MG | 120 | In Stock |
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| 50MG | 222 | In Stock |
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| 100MG | 402 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBenzamil (hydrochloride)
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NoteResearch use only, not for human use.
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Brief DescriptionBenzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
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DescriptionBenzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
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In VitroBenzamil (Benzylamiloride) inhibits neuronal and heterologously expressed small conductance Ca2+-activated K2+ channels.
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In VivoBenzamil (Benzylamiloride) (0.7 mg/kg/day; s.c.) treated stroke-prone spontaneously hypertensive rats (SHRSP) survived, on average, until 16.1 weeks of age in SHRSP rats.
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorENaC
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Research Area——
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Indication——
Chemical Information
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CAS Number2898-76-2
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Formula Weight356.21
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Molecular FormulaC13H15Cl2N7O
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Purity>98% (HPLC)
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Solubility——
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SMILESNc1nc(N)c(nc1Cl)C(=O)NC(=N)NCc1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jeong S Lee S H Kim Y O et al. Antinociceptive Effects of Amiloride and Benzamil in Neuropathic Pain Model Rats[J]. Journal of Korean Medical Science 2013 28(8).
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