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Nonivamide
CAS No. 2444-46-4
Nonivamide ( Pseudocapsaicin;Pelargonic acid vanillylamide;Nonanoic acid vanillylamide )
Catalog No. M13707 CAS No. 2444-46-4
A capsaicin analog that acts as an agonist of TRPV1 channel.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 45 | In Stock |
|
| 500MG | 61 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNonivamide
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NoteResearch use only, not for human use.
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Brief DescriptionA capsaicin analog that acts as an agonist of TRPV1 channel.
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DescriptionA capsaicin analog that acts as an agonist of TRPV1 channel; causes calcium release from the ER and alters the transcription of GADD153, GADD45alpha, GRP78/BiP, ATF3, CCND1, and CCNG2 in human bronchial epithelial and alveolar cells; stimulates the Ca(2+)-dependent release of serotonin and dopamine in SH-SY5Y cells at 1 uM; also enhances miRNA let-7d expression and decreases adipogenesis PPARγ expression in 3T3-L1 cells.Pain Phase 3 Clinical
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SynonymsPseudocapsaicin;Pelargonic acid vanillylamide;Nonanoic acid vanillylamide
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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RecptorTRPV1
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Research AreaNeurological Disease
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IndicationPain
Chemical Information
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CAS Number2444-46-4
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Formula Weight293.40
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Molecular FormulaC17H27NO3
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(NC(CCCCCCCC)=O)C1=CC=C(O)C(OC)=C1
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Chemical NameNonanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rohm B, et al. Mol Nutr Food Res. 2013 Nov;57(11):2008-18.
2. Thomas KC, et al. J Pharmacol Exp Ther. 2007 Jun;321(3):830-8.
3. Rohm B, et al. J Cell Biochem. 2015 Jun;116(6):1153-63.
2. Thomas KC, et al. J Pharmacol Exp Ther. 2007 Jun;321(3):830-8.
3. Rohm B, et al. J Cell Biochem. 2015 Jun;116(6):1153-63.
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