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Nevirapine

CAS No. 129618-40-2

Nevirapine ( BI-RG 587;NSC 641530;NVP )

Catalog No. M11197 CAS No. 129618-40-2

A potent and specific non-nucleoside inhibitor (NNRTI) of HIV-1 reverse transcriptase with Ki of 0.2 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 45 In Stock
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Biological Information

  • Product Name
    Nevirapine
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and specific non-nucleoside inhibitor (NNRTI) of HIV-1 reverse transcriptase with Ki of 0.2 uM.
  • Description
    A potent and specific non-nucleoside inhibitor (NNRTI) of HIV-1 reverse transcriptase with Ki of 0.2 uM; shows no effect on feline and simian RT or any mammalian DNA polymerases; inhibits HIV-1 replication and protein p24 production.HIV Infection Approved
  • Synonyms
    BI-RG 587;NSC 641530;NVP
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV-1reversetranscriptase
  • Research Area
    Infection
  • Indication
    HIV Infection

Chemical Information

  • CAS Number
    129618-40-2
  • Formula Weight
    266.30
  • Molecular Formula
    C15H14N4O
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C1C2=CC=CN=C2N(C3CC3)C4=NC=CC(C)=C4N1
  • Chemical Name
    6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-methyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Merluzzi VJ, et al. Science. 1990 Dec 7;250(4986):1411-3.
2. Cohen KA, et al. J Biol Chem. 1991 Aug 5;266(22):14670-4.
3. Richman D, et al. Antimicrob Agents Chemother. 1991 Feb;35(2):305-8.
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