NSC260594

CAS No. 906718-66-9

NSC260594( NSC 260594 )

Catalog No. M16515 CAS No. 906718-66-9

NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NSC260594
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging.
  • Description
    NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ); specifically blocks HIV-1 RNA encapsidation, binds to HIV-1 gRNA and exhibits potent antiviral activity; NSC260594 also is a small molecule inhibitor of the Escherichia coli condensin MukBEF, affects MukB directly.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 260594
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    906718-66-9
  • Formula Weight
    504.55
  • Molecular Formula
    C29H24N6O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 3.33 mg/mL
  • SMILES
    CN1C=CC(=NC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)N=C4C=CN(C5=C4C=C(C=C5)[N+](=O)[O-])C)C=C1
  • Chemical Name
    4-[(1-methyl-6-nitroquinolin-4-ylidene)amino]-N-[4-[(1-methylpyridin-4-ylidene)amino]phenyl]benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ingemarsdotter CK, et al. Retrovirology. 2018 Mar 14;15(1):25. 2. Zhao H, et al. ACS Infect Dis. 2018 Oct 22. doi: 10.1021/acsinfecdis.8b00222.
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