NSC260594 ( NSC 260594 )

Catalog No. M16515 CAS No. 906718-66-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

NSC260594
Note

Research use only, not for human use.
Brief Description

NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging.
Description

NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ); specifically blocks HIV-1 RNA encapsidation, binds to HIV-1 gRNA and exhibits potent antiviral activity; NSC260594 also is a small molecule inhibitor of the Escherichia coli condensin MukBEF, affects MukB directly.
Synonyms

NSC 260594
Pathway

Microbiology/Virology
Target

HIV
Recptor

HIV
Research Area

——
Indication

——

CAS Number

906718-66-9
Formula Weight

504.55
Molecular Formula

C29H24N6O3
Purity

>98% (HPLC)
Solubility

——
SMILES

CN1C=CC(=NC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)N=C4C=CN(C5=C4C=C(C=C5)[N+](=O)[O-])C)C=C1
Chemical Name

4-[(1-methyl-6-nitroquinolin-4-ylidene)amino]-N-[4-[(1-methylpyridin-4-ylidene)amino]phenyl]benzamide

1. Ingemarsdotter CK, et al. Retrovirology. 2018 Mar 14;15(1):25.
2. Zhao H, et al. ACS Infect Dis. 2018 Oct 22. doi: 10.1021/acsinfecdis.8b00222.

Calculator

molnova catalog