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YYA-021

CAS No. 144217-65-2

YYA-021( YYA 021 | YYA021 )

Catalog No. M11874 CAS No. 144217-65-2

A small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 29 In Stock
25MG 62 In Stock
50MG 84 In Stock
100MG 109 In Stock
200MG 161 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    YYA-021
  • Note
    Research use only, not for human use.
  • Brief Description
    A small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.
  • Description
    A small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity; shows wide tissue distribution and relatively high distribution volumes, and has promise for intravenous administration.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    YYA 021 | YYA021
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    Gp120
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    144217-65-2
  • Formula Weight
    317.4259
  • Molecular Formula
    C18H27N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(NC1CC(C)(C)NC(C)(C)C1)C(NC2=CC=C(C)C=C2)=O
  • Chemical Name
    Ethanediamide, N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hashimoto C, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7884-9. 2. Otsuki H, et al. J Gen Virol. 2013 Dec;94(Pt 12):2710-6. 3. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.
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