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NEO2734

CAS No. 2081072-29-7

NEO2734 ( EP31670 )

Catalog No. M22391 CAS No. 2081072-29-7

NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).

Purity : >98% (HPLC)

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Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
5MG	260	In Stock
10MG	430	In Stock
25MG	710	In Stock
50MG	972	In Stock
100MG	1332	In Stock
500MG	2673	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

NEO2734
Note

Research use only, not for human use.
Brief Description

NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).
Description

NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).NEO2734, a novel dual inhibitor of BET and CBP/p300, is active in both hotspot mutant (F133V) and non-hotspot mutant (Q165P) PCa cells in vitro and in vivo.
Synonyms

EP31670
Pathway

Chromatin/Epigenetic
Target

Epigenetic Reader Domain
Recptor

p300/CBP;BET bromodomain
Research Area

——
Indication

——

Chemical Information

CAS Number

2081072-29-7
Formula Weight

435.44
Molecular Formula

C22H24F3N3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1cc(cn(C)c1=O)-c1ccc2nc(C3CCOCC3)n(CCOC(F)(F)F)c2c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. The novel BET-CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild-type prostate cancer.

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