NCD-25

CAS No. 1456972-46-5

NCD-25( NCD25 | NCD 25 )

Catalog No. M11975 CAS No. 1456972-46-5

NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NCD-25
  • Note
    Research use only, not for human use.
  • Brief Description
    NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM.
  • Description
    NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NCD25 | NCD 25
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    Histone Demethylase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1456972-46-5
  • Formula Weight
    531.7
  • Molecular Formula
    C35H37N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    N-((2S)-1-(benzylamino)-1-oxo-6-((2-phenylcyclopropyl)amino)hexan-2-yl)-[1,1'-biphenyl]-4-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Miyamura S, et al. Org Biomol Chem. 2016 Sep 28;14(36):8576-85. 2. Sugino N, et al. Leukemia. 2017 Nov;31(11):2303-2314. 3. Ogasawara D, et al. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8620-4.
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