NCC-149

CAS No. 1316652-41-1

NCC-149 ( NCC 149;NCC149 )

Catalog No. M11282 CAS No. 1316652-41-1

A potent and selective HDAC8 inhibitor with IC50 of 70 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 231 Get Quote
50MG 1071 Get Quote
100MG 1638 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    NCC-149
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective HDAC8 inhibitor with IC50 of 70 nM.
  • Description
    A potent and selective HDAC8 inhibitor with IC50 of 70 nM; displays high selectivity over major HDACs (HDAC1: IC50 38 uM, HDAC2 >100 uM, HDAC4: IC50: 44 uM,HDAC6: IC50 2.4 uM).
  • Synonyms
    NCC 149;NCC149
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1316652-41-1
  • Formula Weight
    326.37
  • Molecular Formula
    C16H14N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NO)C1=CC=CC(C2=CN(CSC3=CC=CC=C3)N=N2)=C1
  • Chemical Name
    N-hydroxy-3-(1-((phenylthio)methyl)-1H-1,2,3-triazol-4-yl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Suzuki T, et al. ChemMedChem. 2014 Mar;9(3):657-64.
2. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669.
molnova catalog
related products
  • SR-18292

    SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.

  • RGFP966

    RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM in cell-free assay.

  • Remodelin hydrobromi...

    A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.