NCC-149

CAS No. 1316652-41-1

NCC-149 ( NCC 149;NCC149 )

Catalog No. M11282 CAS No. 1316652-41-1

A potent and selective HDAC8 inhibitor with IC50 of 70 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NCC-149
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective HDAC8 inhibitor with IC50 of 70 nM.
  • Description
    A potent and selective HDAC8 inhibitor with IC50 of 70 nM; displays high selectivity over major HDACs (HDAC1: IC50 38 uM, HDAC2 >100 uM, HDAC4: IC50: 44 uM,HDAC6: IC50 2.4 uM).
  • Synonyms
    NCC 149;NCC149
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1316652-41-1
  • Formula Weight
    326.37
  • Molecular Formula
    C16H14N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NO)C1=CC=CC(C2=CN(CSC3=CC=CC=C3)N=N2)=C1
  • Chemical Name
    N-hydroxy-3-(1-((phenylthio)methyl)-1H-1,2,3-triazol-4-yl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Suzuki T, et al. ChemMedChem. 2014 Mar;9(3):657-64.
2. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669.
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