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FT895
CAS No. 2225728-57-2
FT895( FT 895 | FT-895 )
Catalog No. M13554 CAS No. 2225728-57-2
FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 221 | Get Quote |
|
| 50MG | 896 | Get Quote |
|
| 100MG | 1404 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameFT895
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NoteResearch use only, not for human use.
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Brief DescriptionFT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM.
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DescriptionFT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM); displays promising cellular activity (IC50<20 nM) and pharmacokinetic properties; FT895 is a useful tool to study the biology of HDAC11 and shows potential use as a therapeutic target for oncology and inflammation indications.
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In Vitro——
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In Vivo——
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SynonymsFT 895 | FT-895
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number2225728-57-2
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Formula Weight352.317
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Molecular FormulaC16H15F3N4O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (354.80 mM)
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SMILESO=C(NO)C1=C(CN(C2=CN=C(C(F)(F)F)C=N2)C3(C)C)C3=CC=C1
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Chemical NameN-hydroxy-1,1-dimethyl-2-(5-(trifluoromethyl)pyrazin-2-yl)isoindoline-4-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Martin MW, et al. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147.
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