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NBD-556
CAS No. 333353-44-9
NBD-556 ( NBD 556;NBD556 )
Catalog No. M14123 CAS No. 333353-44-9
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | Get Quote |
|
| 5MG | 50 | Get Quote |
|
| 10MG | 87 | Get Quote |
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| 25MG | 146 | Get Quote |
|
| 50MG | 214 | Get Quote |
|
| 100MG | 322 | Get Quote |
|
| 200MG | 475 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNBD-556
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NoteResearch use only, not for human use.
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Brief DescriptionA potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
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DescriptionA potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; inhibits the fusion between HIV-1NL4-3-luc pseudotyped virus expressing HIV-1HXB2 (X4-tropic) envelope and U87-T4-CXCR4 cells with IC50 of 20 uM; inhibits the laboratory-adapted HIV-1 strains IIIB, MN, and V32 with IC50 of 5-16 uM.HIV Infection Preclinical
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SynonymsNBD 556;NBD556
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number333353-44-9
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Formula Weight337.84
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Molecular FormulaC17H24ClN3O2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(NC1CC(C)(C)NC(C)(C)C1)C(NC2=CC=C(Cl)C=C2)=O
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Chemical NameEthanediamide, N1-(4-chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhao Q, et al. Virology. 2005 Sep 1;339(2):213-25.
2. Schn A, et al. Biochemistry. 2006 Sep 12;45(36):10973-80.
3. Curreli F, et al. Antimicrob Agents Chemother. 2014 Sep;58(9):5478-91.
2. Schn A, et al. Biochemistry. 2006 Sep 12;45(36):10973-80.
3. Curreli F, et al. Antimicrob Agents Chemother. 2014 Sep;58(9):5478-91.
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NBD-557
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; inhibits the fusion between HIV-1NL4-3-luc pseudotyped virus expressing HIV-1HXB2 (X4-tropic) envelope and U87-T4-CXCR4 cells with IC50 of 9.7 uM.
