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Home - Products - JAK/STAT Signaling - STAT - N-Methylcytisine

N-Methylcytisine

CAS No. 486-86-2

N-Methylcytisine( Caulophylline )

Catalog No. M18630 CAS No. 486-86-2

N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    N-Methylcytisine
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).
  • Description
    N-Methylcytisine's nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Caulophylline
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    486-86-2
  • Formula Weight
    204.27
  • Molecular Formula
    C12H16N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 120 mg/mL (587.46 mM)
  • SMILES
    CN1CC2CC(C1)C3=CC=CC(=O)N3C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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