
BP-5-087
CAS No. 1803281-30-2
BP-5-087( BP 5-087 )
Catalog No. M12758 CAS No. 1803281-30-2
A potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 963 | Get Quote |
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50MG | 1962 | Get Quote |
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100MG | 2520 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameBP-5-087
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation.
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DescriptionA potent, selective STAT3 SH2 domain inhibitor (EC50=5.6 uM) that reduces STAT3 phosphorylation and nuclear transactivation; restores TKI sensitivity to therapy-resistant CML progenitor cells in primary cells from CML patients with BCR-ABL1 kinase-independent TKI resistance, including leukemic stem cells.
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In Vitro——
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In Vivo——
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SynonymsBP 5-087
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number1803281-30-2
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Formula Weight770.691
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Molecular FormulaC36H30F8N2O6S
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Purity>98% (HPLC)
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Solubility——
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SMILESFC(F)(F)C1=CC=C(S(=O)(N(CC(N(C2=CC=C(C(O)=O)C(O)=C2)CC3=CC=C(C4CCCCC4)C=C3)=O)CC5=C(C)C=CC=C5)=O)C=C1
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Chemical Name4-(N-(4-cyclohexylbenzyl)-2-((N-((perfluorophenyl)methyl)-4-(trifluoromethyl)phenyl)sulfonamido)acetamido)-2-hydroxybenzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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