Cart
sales@molnova.com
Mocetinostat
CAS No. 726169-73-9
Mocetinostat ( MGCD0103;MGCD 0103;MGCD-0103 )
Catalog No. M15781 CAS No. 726169-73-9
An isotype-selective small molecule HDAC inhibitor that selectively inhibits HDAC1 (IC50=0.15 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 32 | In Stock |
|
| 10MG | 47 | In Stock |
|
| 25MG | 72 | In Stock |
|
| 50MG | 90 | In Stock |
|
| 100MG | 142 | In Stock |
|
| 200MG | 185 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMocetinostat
-
NoteResearch use only, not for human use.
-
Brief DescriptionAn isotype-selective small molecule HDAC inhibitor that selectively inhibits HDAC1 (IC50=0.15 uM).
-
DescriptionAn isotype-selective small molecule HDAC inhibitor that selectively inhibits HDAC1 (IC50=0.15 uM); also inhibits HDAC2/3/11; no effect on HDAC4/5/6/7/8; induces hyperacetylation of histones and caused cell cycle blockade in various human cancer cell lines; inhibits growth of human tumor xenografts in nude mice; orally bioactive.Blood Cancer Phase 2 Clinical
-
SynonymsMGCD0103;MGCD 0103;MGCD-0103
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC1;HDAC11;HDAC2;HDAC3;HDAC4
-
Research AreaCancer
-
IndicationBlood cancer
Chemical Information
-
CAS Number726169-73-9
-
Formula Weight396.44
-
Molecular FormulaC23H20N6O
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESNC1=CC=CC=C1NC(=O)C1=CC=C(CNC2=NC=CC(=N2)C2=CN=CC=C2)C=C1
-
Chemical NameBenzamide, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Fournel M, et al. Mol Cancer Ther. 2008 Apr;7(4):759-68.
2. Zhou N, et al. J Med Chem. 2008 Jul 24;51(14):4072-5.
3. Raeppel S, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):644-9.
2. Zhou N, et al. J Med Chem. 2008 Jul 24;51(14):4072-5.
3. Raeppel S, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):644-9.
molnova catalog
related products
-
Ledipasvir
Ledipasvir is a Hepatitis C Virus NS5A Inhibitor. The mechanism of action of ledipasvir is as a P-Glycoprotein Inhibitor, and Breast Cancer Resistance Protein Inhibitor.
-
Apicidin
Apicidin (OSI 2040) is a fungal metabolite that exhibits potent, broad spectrum antiprotozoal activity in vitro.
-
Pracinostat
Pracinostat (SB939) is a potent, orally active HDAC inhibitor that potently inhibits class I, II, and IV HDACsw with Ki of 15-100 nM, inhibits HDAC1 with IC50 of 77 nM.
