![](../../files/images/goods/849234-64-6.png)
Merck60
CAS No. 849234-64-6
Merck60 ( BRD 6929;Compound-60 )
Catalog No. M16166 CAS No. 849234-64-6
Merck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively.
Purity : >98% (HPLC)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
Size | Price / USD | Stock | Quantity |
5MG | 65 | Get Quote |
![]() ![]() |
10MG | 125 | Get Quote |
![]() ![]() |
25MG | 267 | Get Quote |
![]() ![]() |
50MG | 483 | Get Quote |
![]() ![]() |
100MG | 698 | Get Quote |
![]() ![]() |
200MG | Get Quote | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameMerck60
-
NoteResearch use only, not for human use.
-
Brief DescriptionMerck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively.
-
DescriptionMerck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively; displays 50-400 fold selectivity over class I HDAC3 (IC50=458 nM) and no appreciable inhibition of HDAC8 or of the class II HDACs (IC50>30 uM); alters gene expression in brain circuits involved in mood regulation, improves mood-related behaviors in mice.
-
SynonymsBRD 6929;Compound-60
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number849234-64-6
-
Formula Weight351.42
-
Molecular FormulaC19H17N3O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Schroeder FA, et al. PLoS One. 2013 Aug 14;8(8):e71323.
2. Methot JL, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):973-8.
3. Stubbs MC, et al. Clin Cancer Res. 2015 May 15;21(10):2348-58.
2. Methot JL, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):973-8.
3. Stubbs MC, et al. Clin Cancer Res. 2015 May 15;21(10):2348-58.
molnova catalog
![](/themes/theme/en/images/ct.png)
![](/themes/theme/en/images/ct2.png)
related products
-
MC-1575
MC-1575 is a potent and selective class IIa HDAC inhibitor with IC50 of 440 nM for maize HD1-A.
-
Alteminostat
Alteminostat is a novel histone deacetylase (HDAC) inhibitor.
-
PCI-34051
PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM.