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Merck60
CAS No. 849234-64-6
Merck60 ( BRD 6929;Compound-60 )
Catalog No. M16166 CAS No. 849234-64-6
Merck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 65 | Get Quote |
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| 10MG | 125 | Get Quote |
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| 25MG | 267 | Get Quote |
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| 50MG | 483 | Get Quote |
|
| 100MG | 698 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMerck60
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NoteResearch use only, not for human use.
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Brief DescriptionMerck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively.
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DescriptionMerck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively; displays 50-400 fold selectivity over class I HDAC3 (IC50=458 nM) and no appreciable inhibition of HDAC8 or of the class II HDACs (IC50>30 uM); alters gene expression in brain circuits involved in mood regulation, improves mood-related behaviors in mice.
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SynonymsBRD 6929;Compound-60
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number849234-64-6
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Formula Weight351.42
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Molecular FormulaC19H17N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Schroeder FA, et al. PLoS One. 2013 Aug 14;8(8):e71323.
2. Methot JL, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):973-8.
3. Stubbs MC, et al. Clin Cancer Res. 2015 May 15;21(10):2348-58.
2. Methot JL, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):973-8.
3. Stubbs MC, et al. Clin Cancer Res. 2015 May 15;21(10):2348-58.
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