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LMK-235
CAS No. 1418033-25-6
LMK-235 ( LMK 235;LMK 235 )
Catalog No. M11747 CAS No. 1418033-25-6
A selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 41 | In Stock |
|
| 10MG | 65 | In Stock |
|
| 25MG | 128 | In Stock |
|
| 50MG | 222 | In Stock |
|
| 100MG | 402 | In Stock |
|
| 200MG | 593 | In Stock |
|
| 500MG | 888 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLMK-235
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NoteResearch use only, not for human use.
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Brief DescriptionA selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively.
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DescriptionA selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively; less potent for HDAC1/11/2/8; demonstrates activity against chemoresistant cancer cell lines in an MTT assay for cytotoxicity using human ovarian cancer cell lines A2780 and cisplatin resistant A2780CisR (IC50 =0.49 and 0.32 uM respectively).
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SynonymsLMK 235;LMK 235
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC4;HDAC5
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1418033-25-6
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Formula Weight294.35
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Molecular FormulaC15H22N2O4
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 30 mg/mL
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SMILESO=C(NOCCCCCC(NO)=O)C1=CC(C)=CC(C)=C1
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Chemical NameBenzamide, N-[[6-(hydroxyamino)-6-oxohexyl]oxy]-3,5-dimethyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Marek L, et al. J Med Chem. 2013 Jan 24;56(2):427-36.
2. Li A, et al. Eur J Pain. 2013 Sep;17(8):1156-67.
2. Li A, et al. Eur J Pain. 2013 Sep;17(8):1156-67.
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