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Vorinostat
CAS No. 149647-78-9
Vorinostat ( SAHA;Suberoylanilide hydroxamic acid;MK-0683 )
Catalog No. M12074 CAS No. 149647-78-9
A potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 200MG | 40 | In Stock |
|
| 500MG | 77 | In Stock |
|
| 1G | 91 | In Stock |
|
Biological Information
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Product NameVorinostat
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NoteResearch use only, not for human use.
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Brief DescriptionA potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively.
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DescriptionA potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively; inhibits cell growth, induce terminal differentiation and prevent the formation of tumours in mice models.Blood Cancer Approved
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SynonymsSAHA;Suberoylanilide hydroxamic acid;MK-0683
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC;HDAC1;HDAC2;HDAC3;HDAC6;HDAC8
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Research AreaCancer
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IndicationBlood cancer
Chemical Information
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CAS Number149647-78-9
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Formula Weight264.32
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Molecular FormulaC14H20N2O3
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 100 mg/mL
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SMILESO=C(NO)CCCCCCC(NC1=CC=CC=C1)=O
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Chemical NameOctanediamide, N1-hydroxy-N8-phenyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Richon VM, et al. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3003-7.
2. Finnin MS, et al. Nature. 1999 Sep 9;401(6749):188-93.
3. Vrana JA, et al. Oncogene. 1999 Nov 25;18(50):7016-25.
4. Richon VM, et al. Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10014-9.
2. Finnin MS, et al. Nature. 1999 Sep 9;401(6749):188-93.
3. Vrana JA, et al. Oncogene. 1999 Nov 25;18(50):7016-25.
4. Richon VM, et al. Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10014-9.
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