Mal-amido-PEG7-acid ( Mal-NH-PEG7-COOH; Maleimide-NH-PEG7-CH2CH2COOH )

Catalog No. M26749 CAS No. 2112731-42-5

Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Mal-amido-PEG7-acid
Note

Research use only, not for human use.
Brief Description

Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
Description

Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
Synonyms

Mal-NH-PEG7-COOH; Maleimide-NH-PEG7-CH2CH2COOH
Pathway

Others
Target

Other Targets
Recptor

HtrA2
Research Area

——
Indication

——

Chemical Information

CAS Number

2112731-42-5
Formula Weight

548.6
Molecular Formula

C24H40N2O12
Purity

>98% (HPLC)
Solubility

——
SMILES

OC(=O)CCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Cilenti L, et, al. Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2. J Biol Chem. 2003 Mar 28;278(13):11489-94.

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