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MSN-125
CAS No. 1592908-16-1
MSN-125 ( MSN 125;MSN125 )
Catalog No. M12275 CAS No. 1592908-16-1
MSN-125 (MSN 125, MSN125) is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 4 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 710 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMSN-125
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NoteResearch use only, not for human use.
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Brief DescriptionMSN-125 (MSN 125, MSN125) is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 4 uM.
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DescriptionMSN-125 (MSN 125, MSN125) is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 4 uM; potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity.
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SynonymsMSN 125;MSN125
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBcl-2
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Research Area——
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Indication——
Chemical Information
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CAS Number1592908-16-1
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Formula Weight688.62
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Molecular FormulaC36H38BrN3O6
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(N[C@H](C(N([C@@H]1[C@@H](CN)OC2=CC(OCOCCOC)=CC=C12)CC3=CC=C(Br)C=C3)=O)CC4=CC=CC=C4)C5=CC=CC=C5
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Chemical NameN-{1(S)-[[2(R)-Aminomethyl-6-(2-methoxy-ethoxymethoxy)-2,3-dihydro-benzofuran-3(S)-yl]-(4-bromo-benzyl)-carbamoyl]-2-phenyl-ethyl}-benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Niu X, et al.Cell Chem Biol. 2017 Apr 20;24(4):493-506.e5.
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