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BRD1991
CAS No.
BRD1991 ( BRD-1991 )
Catalog No. M17099 CAS No.
BRD1991 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBRD1991
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NoteResearch use only, not for human use.
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Brief DescriptionBRD1991 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
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DescriptionBRD1991 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
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SynonymsBRD-1991
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBcl-2
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight608.56
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Molecular FormulaC33H35Cl2N3O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name3,5-dichloro-N-((10-(1-hydroxypropan-2-yl)-8,12-dimethyl-11-oxo-7,8,9,10,11,12-hexahydro-5H-benzo[9,10][1]oxa[5]azacycloundecino[7,8-b]indol-7-yl)methyl)-N-methylbenzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chiang WC, et al. ACS Chem Biol. 2018 Jun 21. doi: 10.1021/acschembio.8b00421.
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