Cart
sales@molnova.com
MONNA
CAS No. 1572936-83-4
MONNA( —— )
Catalog No. M23684 CAS No. 1572936-83-4
MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | In Stock |
|
| 10MG | 115 | In Stock |
|
| 25MG | 260 | In Stock |
|
| 50MG | 410 | In Stock |
|
| 100MG | 591 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMONNA
-
NoteResearch use only, not for human use.
-
Brief DescriptionMONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM).
-
DescriptionMONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetChloride Channel
-
RecptorTMEM16A
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1572936-83-4
-
Formula Weight338.31
-
Molecular FormulaC18H14N2O5
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESCOC1=CC(=CC2=CC=CC=C21)NC3=C(C=C(C=C3)[N+](=O)[O-])C(=O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.TMEM16A is implicated in the regulation of coronary flow and is altered in hypertension[J]. British Journal of Pharmacology, 2019, 176(11).
molnova catalog
related products
-
T16Ainh-A01
T16Ainh-A01 is an inhibitor of the calcium-activated chloride channel TMEM16A.
-
DCPIB
DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM, demonstrating at least 100-fold higher affinity over TREK1/TRAAK channels.?DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC), has been reported to activate TREK1 and TREK2 in astrocytes and in vitro recently.?
-
IAA-94
IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of epithelial chloride channels that binds channels in bovine kidney cortex microsomes with Ki of 1 uM.
