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ML401

CAS No. 1597489-14-9

ML401( —— )

Catalog No. M22038 CAS No. 1597489-14-9

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .

Purity : >98% (HPLC)

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Size	Price / USD	Stock	Quantity
2MG	174	Get Quote
5MG	260	Get Quote
10MG	410	Get Quote
25MG	678	Get Quote
50MG	954	Get Quote
100MG	1287	Get Quote
500MG	2574	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

ML401
Note

Research use only, not for human use.
Brief Description

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
Description

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
In Vitro

ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM).
In Vivo

ML401 shows very good stability in both human plasma and mouse plasma.
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

GPR
Recptor

GPR183
Research Area

——
Indication

——

Chemical Information

CAS Number

1597489-14-9
Formula Weight

419.74
Molecular Formula

C20H20BrClN2O
Purity

>98% (HPLC)
Solubility

DMSO:10 mg/mL (23.82 mM; Need ultrasonic)
SMILES

C1CN(CCN1CC2=CC=C(C=C2)Cl)C(=O)C=CC3=CC=C(C=C3)Br
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet].

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