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ML401

CAS No. 1597489-14-9

ML401( —— )

Catalog No. M22038 CAS No. 1597489-14-9

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ML401
  • Note
    Research use only, not for human use.
  • Brief Description
    ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
  • Description
    ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
  • In Vitro
    ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM).
  • In Vivo
    ML401 shows very good stability in both human plasma and mouse plasma.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    GPR
  • Recptor
    GPR183
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1597489-14-9
  • Formula Weight
    419.74
  • Molecular Formula
    C20H20BrClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mg/mL (23.82 mM; Need ultrasonic)
  • SMILES
    C1CN(CCN1CC2=CC=C(C=C2)Cl)C(=O)C=CC3=CC=C(C=C3)Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet].
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