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ML399
CAS No. 1560968-49-1
ML399( VU0516340 )
Catalog No. M12219 CAS No. 1560968-49-1
ML399 (VU0516340) is a potent and cell penetrant menin-MLL inhibitor with IC50 of 90 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameML399
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NoteResearch use only, not for human use.
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Brief DescriptionML399 (VU0516340) is a potent and cell penetrant menin-MLL inhibitor with IC50 of 90 nM.
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DescriptionML399 (VU0516340) is a potent and cell penetrant menin-MLL inhibitor with IC50 of 90 nM; shows improved potency and DMPK properties; a chemical probe for in vivo proof-of-mechanism studies.
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In Vitro——
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In Vivo——
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SynonymsVU0516340
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorHMTase
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Research Area——
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Indication——
Chemical Information
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CAS Number1560968-49-1
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Formula Weight445.538
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Molecular FormulaC27H28FN3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESN#CC1=CC=C(OCCCN2CCC([C@@](O)(C3=CC=CC(F)=C3)C4=NC=CC=C4)CC2)C=C1
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Chemical Name(R)-4-(3-(4-((3-Fluorophenyl)(hydroxy)(pyridin-2-yl)methyl)piperidin-1-yl)propoxy)benzonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Senter T, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Senter T, et al. Bioorg Med Chem Lett. 2015 Jul 1;25(13):2720-5.
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