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MS-049
CAS No. 1502816-23-0
MS-049 ( MS049 )
Catalog No. M12091 CAS No. 1502816-23-0
A potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50 of 34±10 nM and 43±7 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 42 | In Stock |
|
| 10MG | 69 | In Stock |
|
| 25MG | 144 | In Stock |
|
| 50MG | 268 | In Stock |
|
| 100MG | 492 | In Stock |
|
| 200MG | 682 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMS-049
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50 of 34±10 nM and 43±7 nM, respectively.
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DescriptionA potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50 of 34±10 nM and 43±7 nM, respectively; displays >30-fold and >300-fold selectivity over PRMT8 and PRMT1/3, does not inhibits PKMTs, DNMTases, RNA methyltransferases; reduces the H3R2me2a mark in HEK293 cells with IC50 of 0.97 uM.
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SynonymsMS049
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorPRMT4;PRMT6
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1502816-23-0
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Formula Weight248.36
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Molecular FormulaC15H24N2O
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 31 mg/mL
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SMILESCNCCN1CCC(OCC2=CC=CC=C2)CC1
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Chemical Name1-Piperidineethanamine, N-methyl-4-(phenylmethoxy)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shen Y, et al. J Med Chem. 2016 Oct 13;59(19):9124-9139.
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