
ML339
CAS No. 2579689-83-9
ML339( —— )
Catalog No. M28860 CAS No. 2579689-83-9
ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 80 | Get Quote |
![]() ![]() |
10MG | 132 | Get Quote |
![]() ![]() |
25MG | 267 | Get Quote |
![]() ![]() |
50MG | 430 | Get Quote |
![]() ![]() |
100MG | 620 | Get Quote |
![]() ![]() |
200MG | Get Quote | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameML339
-
NoteResearch use only, not for human use.
-
Brief DescriptionML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
-
DescriptionML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.(In Vitro):The murine assay was validated using anti-mCXCR16 as an antagonist positive control tested in the presence of an EC80 concentration of mCXCL16 (IC50 = 1.5 nM; % response = 100%). Probe ML339 was shown to be 100-fold less active at the murine CXCR6 receptor using the DiscoveRx β-arrestin cell-based assay format.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetCXCR
-
RecptorCDK9
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2579689-83-9
-
Formula Weight502
-
Molecular FormulaC26H32ClN3O5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 75 mg/mL (149.40 mM)
-
SMILESO=C(NC1=CC=CC=C1Cl)CN2[C@H]3C[C@@H](NC(C4=CC(OC)=C(OC)C(OC)=C4)=O)C[C@@H]2CCC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.
molnova catalog



related products
-
Reparixin L-lysine s...
Reparixin L-lysine salt is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.
-
FC131 TFA (606968-52...
FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.
-
Delmetacin
Delmetacin (Demethacin) is a non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity and inhibitory effects on the CXC chemokine receptor CXCR1.