Cart
sales@molnova.com
Home - Products - Autophagy - CXCR - ML339

ML339

CAS No. 2579689-83-9

ML339( —— )

Catalog No. M28860 CAS No. 2579689-83-9

ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 80 Get Quote
10MG 132 Get Quote
25MG 267 Get Quote
50MG 430 Get Quote
100MG 620 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    ML339
  • Note
    Research use only, not for human use.
  • Brief Description
    ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
  • Description
    ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.(In Vitro):The murine assay was validated using anti-mCXCR16 as an antagonist positive control tested in the presence of an EC80 concentration of mCXCL16 (IC50 = 1.5 nM; % response = 100%). Probe ML339 was shown to be 100-fold less active at the murine CXCR6 receptor using the DiscoveRx β-arrestin cell-based assay format.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    CXCR
  • Recptor
    CDK9
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2579689-83-9
  • Formula Weight
    502
  • Molecular Formula
    C26H32ClN3O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 75 mg/mL (149.40 mM)
  • SMILES
    O=C(NC1=CC=CC=C1Cl)CN2[C@H]3C[C@@H](NC(C4=CC(OC)=C(OC)C(OC)=C4)=O)C[C@@H]2CCC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • AZD8797

    AZD8797 (KAND567) is an orally available, selective and potent human CX3CR1-converting antagonist with inhibitory effects on CX3CR1 and CXCR2.

  • Delmetacin

    Delmetacin (Demethacin) is a non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity and inhibitory effects on the CXC chemokine receptor CXCR1.

  • FC131 TFA (606968-52...

    FC131 TFA is a CXCR4 antagonist that inhibits the binding of [125I] -sdf-1 to CXCR4 with an IC50 value of 4.5 nM and has anti-hiv activity.

Sign In Join Free