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Ajmaline
CAS No. 4360-12-7
Ajmaline( Cardiorythmine | (+)-Ajmaline )
Catalog No. M17726 CAS No. 4360-12-7
Ajmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 37 | In Stock |
|
| 100MG | 59 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAjmaline
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NoteResearch use only, not for human use.
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Brief DescriptionAjmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia.
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DescriptionAjmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and Kv4.3 channels at therapeutic concentrations.
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In VitroElectrophysiological experiments are performed with human embryonic kidney (HEK) cells (whole-cell patch clamp) and Xenopus oocytes (double-electrode voltage clamp) expressing wild-type and mutant HERG channels. Ajmaline blocks HERG currents with an IC50 of 1.0μM in HEK cells and 42.3μM in Xenopus oocytes.
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In Vivo——
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SynonymsCardiorythmine | (+)-Ajmaline
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PathwayAutophagy
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TargetCXCR
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Recptorsodium channel
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number4360-12-7
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Formula Weight326.4
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Molecular FormulaC20H26N2O2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 66 mg/mL; 202.19 mM
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SMILESCC[C@H]1[C@@H]2C[C@H]3[C@@H]4N(C)c5ccccc5[C@]44C[C@@H](C2[C@H]4O)N3[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fischer F, et al. Naunyn-Schmiedeberg's Archives of Pharmacology, 2013, 386(11):991-999.
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