Cart
sales@molnova.com
Home - Products - Autophagy - CXCR - Ajmaline

Ajmaline

CAS No. 4360-12-7

Ajmaline( Cardiorythmine | (+)-Ajmaline )

Catalog No. M17726 CAS No. 4360-12-7

Ajmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 37 In Stock
100MG 59 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Ajmaline
  • Note
    Research use only, not for human use.
  • Brief Description
    Ajmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia.
  • Description
    Ajmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and Kv4.3 channels at therapeutic concentrations.
  • In Vitro
    Electrophysiological experiments are performed with human embryonic kidney (HEK) cells (whole-cell patch clamp) and Xenopus oocytes (double-electrode voltage clamp) expressing wild-type and mutant HERG channels. Ajmaline blocks HERG currents with an IC50 of 1.0μM in HEK cells and 42.3μM in Xenopus oocytes.
  • In Vivo
    ——
  • Synonyms
    Cardiorythmine | (+)-Ajmaline
  • Pathway
    Autophagy
  • Target
    CXCR
  • Recptor
    sodium channel
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    4360-12-7
  • Formula Weight
    326.4
  • Molecular Formula
    C20H26N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 66 mg/mL; 202.19 mM
  • SMILES
    CC[C@H]1[C@@H]2C[C@H]3[C@@H]4N(C)c5ccccc5[C@]44C[C@@H](C2[C@H]4O)N3[C@@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fischer F, et al. Naunyn-Schmiedeberg's Archives of Pharmacology, 2013, 386(11):991-999.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • AZD8797

    AZD8797 (KAND567) is an orally available, selective and potent human CX3CR1-converting antagonist with inhibitory effects on CX3CR1 and CXCR2.

  • Ulocuplumab

    Ulocuplumab (BMS-936564) is a fully human anti-CXCR4 IgG4 antibody.Ulocplumab exhibits antitumor activity in acute myeloid leukemia (AML), non-Hodgkin's lymphoma (NHL), and multiple myeloma transplantation models.

  • Reparixin L-lysine s...

    Reparixin L-lysine salt is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.

Sign In Join Free