ML-193

CAS No. 713121-80-3

ML-193 ( CID 1261822 )

Catalog No. M24723 CAS No. 713121-80-3

ML-193 is a potent and selective GPR55 antagonist( IC50 : 221 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 72 In Stock
10MG 125 In Stock
25MG 258 In Stock
50MG 410 In Stock
100MG 605 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ML-193
  • Note
    Research use only, not for human use.
  • Brief Description
    ML-193 is a potent and selective GPR55 antagonist( IC50 : 221 nM).
  • Description
    ML-193 is a potent and selective GPR55 antagonist( IC50 : 221 nM). It shows more than 27-fold selectivity for GPR55 over GPR35, CB1 and CB2, and can improve the motor and the sensorimotor deficits of Parkinson’s disease (PD) rats.
  • Synonyms
    CID 1261822
  • Pathway
    GPCR/G Protein
  • Target
    Cannabinoid Receptor
  • Recptor
    GPR55
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    713121-80-3
  • Formula Weight
    527.6
  • Molecular Formula
    C28H25N5O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1c(NS(c(cc2)ccc2NC(c2cc(-c3ncccc3)nc3c(C)cc(C)cc23)=O)(=O)=O)onc1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fatemi I, et, al. The effect of intra-striatal administration of GPR55 agonist (LPI) and antagonist (ML193) on sensorimotor and motor functions in a Parkinson's disease rat model. Acta Neuropsychiatr. 2021 Feb;33(1):15-21.
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