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AM251
CAS No. 183232-66-8
AM251 ( AM251; AM 251; AM-251 )
Catalog No. M12824 CAS No. 183232-66-8
AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors; also potent GPR55 agonist (EC50 = 39 nM).
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
|
| 10MG | 65 | In Stock |
|
| 25MG | 119 | In Stock |
|
| 50MG | 212 | In Stock |
|
| 100MG | 313 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAM251
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NoteResearch use only, not for human use.
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Brief DescriptionAM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors; also potent GPR55 agonist (EC50 = 39 nM).
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DescriptionAM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors; also potent GPR55 agonist (EC50 = 39 nM).
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SynonymsAM251; AM 251; AM-251
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCB1
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number183232-66-8
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Formula Weight555.24
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Molecular FormulaC22H21Cl2IN4O
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Purity>98%(HPLC)
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SolubilityDMSO: 40 mg/mL (72.04 mM)
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SMILESO=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(I)C=C3)=C1C)NN4CCCCC4
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Chemical Name1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Thewke D, et al. Biochem Biophys Res Commun, 2009, 381(2), 181-186.
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